Yuezhou Zhang, Amos Folarin, Rongrong Zhong, Hyunju Kim, Callum Stewart, Shaoxiong Sun, Richard Dobson
We characterized long-term, objectively measured physical activity trajectories surrounding total knee arthroplasty (TKA) and total hip arthroplasty (THA) and examined factors associated with wearable-derived physical activity recovery. In this observational study within the All of Us Research Program, linked electronic health records and Fitbit step count data spanning the two years before and the two years after surgery were analyzed using piecewise linear mixed-effects models to characterize preoperative and postoperative trajectories. Recovery of physical activity was defined relative to two preoperative baselines-activity measured immediately before surgery and a more remote baseline approximating longer-term habitual activity-and associated factors were examined using Cox proportional hazards models. Among 238 participants (147 TKA, 91 THA; mean age 64.9 [SD 8.3] years), both procedures showed progressive preoperative decline, with accelerated decline beginning earlier in TKA than in THA. Postoperative recovery followed a staged pattern, with rapid early improvement, slower intermediate gains, and later stabilization. Recovery to the immediate preoperative baseline occurred earlier than recovery to the remote baseline. Higher activity during the 4 weeks before surgery was associated with a greater likelihood of recovery to the remote baseline. These findings support long-term wearable monitoring as a complementary measure of physical activity recovery after arthroplasty.