Transesterification/Esterification Reaction Catalysed by Functional Hybrid MOFs for Efficient Biodiesel Production

Biodiesel is an alternative, sustainable, renewable, and environmentally friendly energy source, which has generated interest from the scientific community due to its low toxicity, rapid biodegradability, and zero carbon footprint. Biodiesel is a biofuel produced by the transesterification of triglycerides or the esterification of free fatty acids (FFA). Both reactions require catalysts with numerous active sites (basic, acidic, bifunctional, or enzymatic) for efficient biodiesel production. On the other hand, since the late 1990s, metal–organic frameworks (MOFs) have emerged as a new class of porous materials and have been successfully used in various fields due to their multiple properties. For this reason, MOFs have been used as heterogeneous catalysts or as a platform for designing active sites, thus improving stability and reusability. This literature review presents a comprehensive analysis of using MOFs as heterogeneous catalysts or supports for biodiesel production. The optimal parameters for transesterification/esterification are detailed, such as the alcohol/feedstock molar ratio, catalyst amount, reaction time and temperature, conversion percentage, biodiesel yield, fatty acid and water content, etc. Additionally, novel methodologies such as ultrasound and microwave irradiation for obtaining MOF-based catalysts are described. It is important to note that most studies have shown biodiesel yields >90% and multiple reuse cycles with minimal activity loss. The bibliographic analysis was conducted using the American Chemical Society (ACS) Scifinder® database, the Elsevier B.V. Scopus® database, and the Clarivate Analytics Web of Science® database, under the institutional license of the Universidad Veracruzana. Keywords were searched for each section, generally limiting the document type to “reviews” and “journals,” and the language to English, and published between 2000 and 2025.