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◆ Microorganisms2026-07-24

Recent Advances in Encapsulation Strategies for Synbiotic Formulation Containing Lactiplantibacillus plantarum.

Kairat Saparkhanovich Zhakipbekov, Murat Zulpidinovich Ashirov, Baurzhan Kalzhanovich Makhatov, Karlygash Manapovna Akpayeva, Aziza Mukataikyzy Omari, Rakatzhan Duisenbekuly Abdikalykov, Zhanar Kasymbekovna Shimirova, Gulmira Marsovna Abdrakhmanova, Yerbolat Abibillayevich Tulebayev, Sabit Bekseitovich Pazilov, Bazarkhan Imangaliyeva, Marzhan Bauyrzhan, Bauyrzhan Kuanishbekovich Toizhanov, Zhanat Sadebekovna Toxanbayeva, Sulushash Dauletiyarkyzy Butanbayeva

原始摘要(英文原文)· Original abstract
Lactiplantibacillus plantarum is one of the most studied probiotic organisms due to its adaptability, gastrointestinal tolerance, antimicrobial activity, and health-promoting properties. However, the survival and efficacy of this probiotic can be significantly reduced during processing, storage, and gastrointestinal transit, limiting its effectiveness in food, nutraceutical, and pharmaceutical products. Synbiotic formulations, which are prepared by combining probiotics with prebiotics, have emerged as a promising approach to enhance the survival and efficacy of probiotics. In this context, encapsulation technologies play a crucial role in protecting probiotic cells from environmental and physiological stresses and in enabling controlled release at targeted sites within the gastrointestinal tract. This review describes recent developments in encapsulation strategies for L. plantarum-based synbiotic formulations, including traditional methods such as spray drying, freeze drying, extrusion and emulsion-based systems, as well as emerging methods such as nanoencapsulation and hydrogel-based delivery systems. The properties of commonly used encapsulating materials, and functional applications in food, nutraceutical and pharmaceutical products are also described. Furthermore, current challenges and future prospects are also highlighted. Overall, encapsulation represents an effective strategy to improve the stability, delivery and therapeutic potential of L. plantarum-based synbiotic formulations.
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Recent Advances in Encapsulation Strategies for Synbiotic Formulation Containing Lactiplantibacillus plantarum. — 科研速览 Science Skim