Photonic Crystal Fiber–Based Surface Plasmon Resonance Sensor for Precise Biochemical Refractive Index Sensing

In this work, a D-shaped Photonic Crystal Fiber (PCF) sensor with a detection range of 1.30–1.35 is proposed, including Gold (Au), Titanium Dioxide (TiO2), graphene, and a functionalized sensing region. Instead of filling or coating inside the PCF’s air holes, the Gold (Au) layer is applied to the polished surface. The effects of the larger air holes’ diameter and the thickness of the Au layer are examined. To achieve effective RI sensing, the proposed design leverages the strong coupling between the core mode and the Surface Plasmon (SP) excitation mode. Modal dispersion, confinement loss, and electric field distributions are analyzed for analyte RI values ranging from 1.30 to 1.35 using the Finite Element Method (FEM). The sensor demonstrates improved plasmonic excitation with a maximum Wavelength Sensitivity (WS) of 3000 nm/RIU (Au = 45 nm), strong confinement loss of more than 788.39 dB/cm (at Au = 40 nm), and a highest Figure of Merit (FoM) of 62.5/RIU (at Au = 40 nm with RI = 1.32). The TiO2 layer enhances mode coupling and resonance sharpness, while the optimized Au thickness boosts sensitivity and spectral resolution. Additionally, the blood components reach the WS of 5000 nm/RIU for plasma and 3000 nm/RIU for Krypton. Because of its high tunability and repeatable performance, the PCF–SPR biosensor is a promising choice for precise biochemical and biomedical sensing applications.