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◆ European journal of applied physiology2026-09-24

Effects of different sodium bicarbonate supplementation strategies on repeated 3-min all-out cycling performance and blood acid-base responses.

Xiaolin Yang, Qian Yang, Zihong He, Dapeng Bao, Xun Jiang, Lars McNaughton

一句话结论 · In one sentence

SB supplementation increased overall WEP across repeated 3MTs, although the ergogenic effects were more evident during the first bout. Divided ingestion of 0.4 g·kg- 1 body mass may provide the most favorable balance between ergogenic benefit and gastrointestinal tolerance.

原始摘要(英文原文)· Original abstract
PURPOSE: This study compared four sodium bicarbonate (SB) supplementation strategies differing in dose and dosing pattern on end-test power (EP), work performed above EP (WEP), and blood acid-base responses during two 3-min all-out cycling tests (3MTs) separated by 70 min. METHODS: Sixteen trained men completed a randomized crossover study involving four SB conditions: single-dose moderate-SB (SM-SB), multiple-dose moderate-SB (MM-SB), single-dose higher-SB (SH-SB), and multiple-dose higher-SB (MH-SB), and placebo (PLA). The SB conditions comprised 0.3-0.4 g·kg⁻¹ body mass administered as a single or multiple dose. Ninety minutes after supplementation, participants performed two 3MTs separated by 70 min, with blood variables measured before and after each bout and during recovery. RESULTS: Overall WEP showed significant main effects of supplementation condition (F = 4.10, ηp² = 0.11, P < 0.05) and time (F = 13.50, ηp² = 0.09, P < 0.05), with no significant condition × time interaction. During 3MT1, WEP was higher with SM-SB and MH-SB than PLA (~ 17.9% and ~ 18.6%, respectively; P < 0.05), with a significant condition main effect. Whereas during 3MT2, WEP was higher with SH-SB than PLA (~ 15.7%, P < 0.05), despite no significant condition main effect. EP showed no supplementation condition × time interaction (F = 0.60, ηp² = 0.02, P > 0.05) or supplementation condition main effect, but differed between 3MT1 and 3MT2 (F = 11.07, ηp² = 0.08, P < 0.05). A significant supplementation condition × time interaction was observed for blood [HCO3⁻] (P < 0.05). All SB conditions resulted in higher [HCO3⁻] than PLA before both 3MTs (P < 0.05), with no differences among SB conditions. Lactate also showed a significant supplementation condition × time interaction (F = 1.82, ηp² = 0.08, P < 0.05), with higher concentrations immediately after both 3MTs in all SB conditions than PLA (P < 0.05). CONCLUSION: SB supplementation increased overall WEP across repeated 3MTs, although the ergogenic effects were more evident during the first bout. Divided ingestion of 0.4 g·kg- 1 body mass may provide the most favorable balance between ergogenic benefit and gastrointestinal tolerance.
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Effects of different sodium bicarbonate supplementation strategies on repeated 3-min all-out cycling performance and blood acid-base responses. — 科研速览 Science Skim