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◆ Molecules (Basel, Switzerland)2026-08-11

Metal-Free Oxidative Functionalization of Allylic Sulfones/Allylic Triflones with Water Participation Enabled by Hypervalent Iodine Reagents.

Qian Tong, Li-Ting Xiao, Ming-Yang Gu, Xue-Qiang Chu, Danhua Ge

原始摘要(英文原文)· Original abstract
A metal-free, efficient, iodine(III)-promoted oxidative transformation of allylic sulfones/allylic triflones with water participation for accessing sulfonyl ketones and triflyl allylic alcohols is reported. This strategy enables the selective construction of two SO2-containing compounds with chemical and biological significance, and its success mainly relies on the substitution effect of the starting materials. Water serves as an eco-friendly oxygen atom source. This transformation has excellent selectivity, broad substrate scope, mild reaction conditions, and ease of scale-up.
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Metal-Free Oxidative Functionalization of Allylic Sulfones/Allylic Triflones with Water Participation Enabled by Hypervalent Iodine Reagents. — 科研速览 Science Skim