Polymicrobial Catheter-Related Bloodstream Infection Involving Brevundimonas diminuta and Streptococcus anginosus: A Case Report and Literature Review.

Catheter-related bloodstream infections (CRBSIs) caused by Brevundimonas diminuta are rare, and polymicrobial infections involving this organism are exceptionally uncommon. To the best of our knowledge, we describe the first reported case of polymicrobial CRBSI caused by B. diminuta and Streptococcus anginosus in a woman with a pituitary gland tumor and intracranial hypertension who was receiving intravenous treatment through an indwelling peripherally inserted central catheter (PICC). The patient made a full clinical recovery after prompt PICC removal and intravenous piperacillin-tazobactam therapy. This case emphasizes the emerging clinical significance of B. diminuta and S. anginosus as potential causes of polymicrobial bloodstream infection in patients with indwelling central venous catheters and underlines the need to consider uncommon environmental Gram-negative organisms in catheter-related infection.