Hiroaki Kimura, Tadashi Kobayashi, Ryoya Asaka, Hideaki Obata
Background and Objectives: Non-odontogenic toothache often persists without an identifiable dental cause and may lead to unnecessary pulpectomy or tooth extraction. It may also result in long-term combined use of psychotropic medications, forming a recurrent clinical pattern. Ultrasound-guided fascia hydrorelease (US-FHR) targeting fascia-derived pathology has been applied to non-odontogenic toothache; however, treatment regions have not been systematically described. This article presents a proposed eleven-point US-FHR protocol for non-odontogenic toothache and related orofacial pain. Materials and Methods: This is an experience-based clinical protocol; it is not an efficacy study and does not include a new prospective study on human participants. The protocol was organized on the basis of long-term clinical experience at Kimura Pain Clinic and a focused literature search. Results: The protocol comprises 11 POINTs distributed across six anatomical regions: (1) three POINTs in the masticatory muscle region, (2) three POINTs in the medial pterygoid and capsular region, (3) one POINT in the parotid region, (4) two POINTs in the cervical region, (5) one POINT in the facial-artery region, and (6) one POINT in the upper posterior cervical region. For each POINT, the anatomical rationale, referred-pain pattern, procedural concept, and safety considerations are described. Conclusions: The proposed eleven-point protocol represents an expanded and structured development of the earlier four-region approach. Prospective, ideally controlled, studies are needed to evaluate its clinical effectiveness.