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◆ Frontiers in endocrinology2026-01-01

Post-thyroidectomy anterior neck dysfunction: clinical phenotypes, mechanisms, and comprehensive management.

Xiaokang Liu, Yu Li, Qiang Ma, Lijuan An, Liang Guo

原始摘要(英文原文)· Original abstract
Thyroid surgery is generally safe; however, satisfactory postoperative recovery is not determined solely by traditional complications such as recurrent laryngeal nerve injury, bleeding, or hypocalcemia. A subset of patients develop interrelated symptoms-including voice changes, swallowing discomfort, anterior neck pain or tightness, restricted cervical mobility, and sensory abnormalities-that are considered here within a proposed framework of post-thyroidectomy anterior neck dysfunction. In this review, the term is used as a working conceptual framework rather than a formally established diagnostic entity. Plausible mechanisms include neural injury, anterior neck muscle injury, restricted laryngotracheal motion, adhesion and fibrosis, and altered sensory input. Using a structured narrative synthesis of the available literature, we summarize the clinical phenotypes, natural history, potential mechanisms, risk factors, assessment tools, and prevention and treatment strategies relevant to this framework.
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Post-thyroidectomy anterior neck dysfunction: clinical phenotypes, mechanisms, and comprehensive management. — 科研速览 Science Skim