Savannah G Moore, Maxmillian J Field, Logan S D'Souza
Although benign, cutaneous pseudoepitheliomatous hyperplasia (PEH) is oftentimes difficult to distinguish from squamous cell carcinoma (SCC). PEH arises from underlying dermal neoplasia, infection, or inflammation. This case report presents the case of a patient with PEH that occurred as a reactive inflammatory response to a foreign body canine hair, which was originally misdiagnosed as SCC. This case highlights a unique etiology of PEH and the importance of using the patient's social history, physical examination, and appropriate biopsy considerations in complex dermatologic cases where pathology alone is not definitive.