Microplastics and Antimicrobial Resistance Genes in Surface Waters Under European Union Regulatory Progress

Microplastics (MPs) and antimicrobial resistance genes (ARGs), emerging pollutants in surface waters, are viewed as a serious risk to freshwater ecosystems and public health. This review synthesizes current scientific knowledge, regulatory approaches, and monitoring methodologies on the presence and impact of these contaminants following a drivers-pressures-state-impact-response (DPSIR) framework. Major anthropogenic factors, such as pharmaceutical consumption and agricultural intensification, are putting pressure on water bodies through industrial discharges, agricultural runoff, and untreated or inadequately treated wastewaters. In order to gauge the current environmental state and discuss the impact on human and ecosystem health within a One Health framework, it is necessary to generate monitoring data and identify methodological gaps in the interaction between MPs and ARGs. Despite recent European Union (EU) regulatory progress, such as the Drinking Water Directive and the Water Framework Directive, substantial gaps remain in methodology standardization as well as practical implementation. This review underscores the need to establish enforceable thresholds and standardize monitoring protocols to effectively mitigate the growing prevalence and consequences of these contaminants.