Resveratrol for Cancer Treatment: Effects on Metabolism and Immune Cells

Resveratrol is a natural polyphenol found in plants that has attracted significant research attention for its antitumor potential. With the continuing research on the tumor microenvironment and metabolic reprogramming, the roles of resveratrol in tumor cell metabolism and immune cell function have gained increasing attention. Recent studies have shown that resveratrol disrupts tumor cell metabolism and prevents tumor cell growth and metastasis by inhibiting metabolic processes such as glycolysis and fatty acid production. Furthermore, resveratrol regulates immune cells such as T cells, macrophages, and natural killer cells and enhances antitumor immune responses. In this article, we report the recent research progress on the use of resveratrol for tumor therapy. Specifically, we focus on its regulatory effect on tumor metabolism and the immune microenvironment and discuss its potential in combination with a new therapeutic strategy.