Angelica Zaninelli Schreiber, Ana Luisa Perini Leme Giordano, Barbara Cipulo Legabão, Lais Pontes, Edson Aparecido da Luz, Giuliana D'Angelo Moreno, Gisele Giuliane Guedes, Stefânia Lucizani Pacífico, Mariana Marques Fernandes Moreira de Souza, Tânia Sueli de Andrade, Carolina Carvalho Ribeiro do Valle, Jamil Pedro de Siqueira Caldas
Early diagnosis, serial susceptibility testing, and immediate containment measures enabled successful treatment and prevented nosocomial spread.
PURPOSE: To describe the first neonatal invasive Candida auris infection in Brazil and its successful clinical and infection control management.
METHODS: Retrospective description of the clinical course, microbiological findings, antifungal susceptibility evolution, and follow-up of an extremely preterm infant.
RESULTS: A 25 + 4-week male neonate developed bloodstream and urinary C. auris infection during the first week of life. Progressive amphotericin B resistance in urine isolates required the addition of fluconazole. No secondary NICU cases occurred.
CONCLUSION: Early diagnosis, serial susceptibility testing, and immediate containment measures enabled successful treatment and prevented nosocomial spread.