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◆ Hasvet Journal of Veterinary Medicine2026-08-17· Disease

Cross-Species Neurodegenerative Processes in Dogs and Humans: A Comparative Analysis of Alzheimer’s Disease and Canine Cognitive Dysfunction Syndrome

Hilal Kurum

原始摘要(英文原文)· Original abstract
he thousands of years of parallel evolution and domestication shared by humans and dogs have brought the brain development of both species, and their susceptibility to age-related cellular degeneration, to a common point.Agerelated cognitive dysfunction in dogs shows a substantial parallel with Alzheimer's disease in humans, both in terms of clinical signs and structural changes in the brain.Within the framework of a One Health approach, the joint study of these two species-which share the same environmental conditions and have been companions for centuries-carries critical potential both for improving the quality of life of dogs and for developing new and effective treatments for Alzheimer's disease, one of humanity's greatest medical challenges.
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Cross-Species Neurodegenerative Processes in Dogs and Humans: A Comparative Analysis of Alzheimer’s Disease and Canine Cognitive Dysfunction Syndrome — 科研速览 Science Skim