Dario Palescandolo, Sohaib Ali, Alessandro Melatini, Marilena Rolli, Domenico Cassitto, Alessandra Giaquinta, Francesco Mastromatteo, Manfredo Esposito, Mariagrazia Nizzola, Kumail Ali, Haleema Sadia, Vittorio Voena, Antonio Ruggieri, Gianfreda Cosimo Damiano
Rarely, MHE spinal osteochondromas cause spinal cord compression that is readily relieved with typical decompressive procedures.
BACKGROUND: Multiple hereditary exostoses (MHE) is a rare autosomal dominant disorder. It is characterized by the development of cartilage-capped bony outgrowths arising from the epiphyseal or diaphyseal regions of long bones, leading to reduced joint motion and pain secondary to compression. MHE is attributed to the predominant exostin-1 and exostin-2 mutations that cause multiple osteochondromas. The most common locations of these lesions are on the knee joint, humerus, pelvis, scapula, and also the spine.
CASE DESCRIPTION: A 26-year-old Caucasian male with a diagnosis of MHE, presenting with progressive spastic tetraparesis. The cervical magnetic resonance (MR) revealed an osteochondroma arising from the C2 lamina dorsolaterally compressing the spinal cord at the C1-C2 level. Following a C2 laminectomy, the postoperative MR imaging confirmed gross total lesion excision. Postoperatively, the patient's myelopathy gradually improved and was discharged to a rehabilitation facility.
CONCLUSION: Rarely, MHE spinal osteochondromas cause spinal cord compression that is readily relieved with typical decompressive procedures.