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◆ Indian Journal of Nuclear Medicine2026-04-10· Medicine

Targeting the Untargetable: [ <sup>161</sup> Tb]Tb-FAP-2286 in Young-Onset Refractory Cholangiocarcinoma

Swagat Dash, Vindhya Malasani, Rakhee Vatsa, Majid Assadi, Habibollah Dadgar, Hossein Arabi, Amit Verma, Dinesh Pendharkar

原始摘要(英文原文)· Original abstract
Paediatric and adolescent cholangiocarcinoma (CCC) is extremely rare, and an advanced-stage diagnosis precludes surgical intervention as a primary treatment. Therefore, early diagnosis and precise staging are critical for improving patient outcomes. A pronounced desmoplastic reaction is the hallmark of cholangiocarcinoma, positioning FAPI as a promising theragnostic approach for patients unresponsive to conventional therapies. We present a case of young-onset refractory cholangiocarcinoma, refractory to multiple treatment lines, administered [ 161 Tb]Tb-FAP-2286, exhibiting a partial response.
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Targeting the Untargetable: [ <sup>161</sup> Tb]Tb-FAP-2286 in Young-Onset Refractory Cholangiocarcinoma — 科研速览 Science Skim