Wenbo Xu, Lufeng Yao, Haigang Wang, Chenqin Xu, Pinpin He, Yi Zhang, Jiasong Pan, Shengdi Lu, Lei Huang
Home-based digital exercise was non-inferior for 3-month first-step pain and less costly from both perspectives. Matching left 12 of 13 covariates imbalanced and only 6.3% of screened patients were eligible, so residual confounding and selection bias are likely. These observational findings are provisional and require confirmation in a pragmatic multicentre randomized controlled trial before informing reimbursement.
OBJECTIVE: To compare the clinical effectiveness and cost-effectiveness of a 12-week home-based digital exercise programme with 12-week hospital-supervised physiotherapy for plantar fasciitis in routine Chinese tertiary-hospital care.
DESIGN: Single-centre retrospective cohort study with 1:2 propensity-score matching on 13 baseline covariates.
SUBJECTS/PATIENTS: 587 adults with a clinician-confirmed diagnosis of plantar fasciitis treated in 2022-2024 were matched.
METHODS: The primary outcome was first-step morning pain at 3 months on a 0-10 numeric rating scale (non-inferiority margin 1.3 points; sensitivity margins 0.9 and 1.9). A 12-month cost-utility analysis took payer and societal perspectives.
RESULTS: The adjusted mean difference was -0.63 points (95% confidence interval -0.92 to -0.35; p < 0.001), non-inferior against all 3 margins (E-value 2.84). Incremental payer cost was -¥4,920 (-US$684), incremental societal cost -¥7,008 (-US$974), and incremental quality-adjusted life-years +0.011, with dominance in 96.7% of bootstrap replications.
CONCLUSION: Home-based digital exercise was non-inferior for 3-month first-step pain and less costly from both perspectives. Matching left 12 of 13 covariates imbalanced and only 6.3% of screened patients were eligible, so residual confounding and selection bias are likely. These observational findings are provisional and require confirmation in a pragmatic multicentre randomized controlled trial before informing reimbursement.