Shaowei Zheng, Dun Liu, Yilong Fu, Di Chen, Dongming Yan
Collision tumors in the sellar region are uncommon, most frequently composed of pituitary adenomas and Rathke's cleft cysts. However, the coexistence of a craniopharyngioma and a pituitary adenoma represents an exceedingly rare entity. Here, we report a unique case of a 60-year-old woman presenting with progressive bilateral visual decline. Neuroimaging identified distinct sellar and suprasellar masses. The patient underwent endoscopic endonasal surgery with gross total resection (GTR). Postoperative histopathological analysis confirmed a collision tumor consisting of a papillary craniopharyngioma and a thyrotropin (TSH)-secreting pituitary adenoma. To the best of our knowledge, this is the first documented case of coexisting papillary craniopharyngioma and TSH-secreting pituitary adenoma in the sellar region.