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◆ Clinical Cosmetic and Investigational Dermatology2026-02-01· Medicine

Treatment for Filler-Induced Alopecia with Concentrated Growth Factors

LiHong Zhang, JianKe Li, Xi’An Fu, Hong Liu, FuRen Zhang

原始摘要(英文原文)· Original abstract
Hyaluronic acid (HA) is widely used for non-surgical facial rejuvenation but is associated with risks, including rare filler-induced alopecia (FIA) in the temporal and frontal regions. While subcutaneous hyaluronidase (HAase) injection is the standard treatment, we report an alternative approach using concentrated growth factor (CGF) injections. A 29-year-old female presented with a pruritic alopecic patch in the right temporal region that appeared 20 days after receiving HA filler injection. A well-demarcated 6×4 cm alopecic patch persisted despite prior treatment with HAase. The patient subsequently underwent four CGF injections. During the ten-month follow-up, significant hair regrowth was observed. This case suggests that CGF monotherapy is a promising treatment for FIA.
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