This report highlights a case of unilateral vortex keratopathy in a patient utilising diclofenac emulgel, highlighting the rare occurrence of corneal deposits secondary to topical nonsteroidal anti-inflammatory drugs (NSAIDs).This article presented a 77-year-old male with multiple systemic comorbidities who was on regular follow-ups in the ophthalmology clinic for bilateral pseudoexfoliative glaucoma and left eye polypoidal choroidal vasculopathy.He was noted to have grayish deposits on his left eye cornea epithelium during one of the visits, prompting suspicion of unilateral vortex keratopathy.He did not have any visual symptoms during the presentation.His best-corrected visual acuity of the left eye was 6/36 which was attributed to the foveal scarring and pigment epithelial detachment as complications of polypoidal choroidal vasculopathy.The best-corrected the visual acuity of the right eye was 6/12 with no sign of vortex keratopathy.For the past two years, he has been using diclofenac emulgel on