Sunčica Humačkić, Marko Pavlović, Martina Krešić Ćorić, Ivana Sušac
The findings suggest that inflammation, as indicated by elevated NLR, is linked to SSD independent of MS.
AIM: To investigate the differences in neutrophil-to-lymphocyte ratio (NLR) between patients with schizophrenia spectrum disorders (SSD) and healthy controls, and their association with metabolic syndrome (MS) in SSD patients.
METHODS: A cross-sectional study was conducted involving 70 SSD patients and 55 healthy controls. NLR was calculated using absolute neutrophil and lymphocyte counts (WBC) after obtaining complete blood counts. MS was diagnosed using ATP III criteria, and SSD patients were divided into two subgroups with and without MS.
RESULTS: Patients with SSD had significantly higher total WBC (p = 0.001), as well as neutrophil counts and NLR (both p 0.05).
CONCLUSION: The findings suggest that inflammation, as indicated by elevated NLR, is linked to SSD independent of MS.