Luiz Gonzaga Vaz Coelho, Bruno Squárcio Fernandes Sanches, Ismael Maguilnik, James Ramalho Marinho, Sandro Rodrigues Chaves, Ana Flávia P Ramos, Heinrich Seidler, Ricardo C Barbuti, Renato S Laboissière, Laércio Tenório Ribeiro, Maria do Carmo F Passos, Julio César de Soares Veloso, Lucia Libanês C Braga, Frederico Passos Marinho, Helenice P Breyer, Hoiti Okamoto, Jardel Soares Caetano, Paulo Pimentel D'Assumpção, Leonardo Soares da Silva, Gerson Domingues, Raul Carlos Wahle, Eliza Maria de Brito, Marcela Tavares da Rocha Loures, Joaquim Prado Moraes-Filho, Décio Chinzon, Áureo Almeida Delgado
The groups developed 34 evidence-based recommendations to guide clinicians in managing this infection within the Brazilian population.
BACKGROUND: Helicobacter pylori infection remains highly prevalent, affecting approximately 40% of the global population. Individuals with infection continue to be at risk for its various clinical consequences, including chronic gastritis, peptic ulcer disease, and gastric cancer.
OBJECTIVE: The Brazilian Helicobacter pylori and Microbiota Study Group and the Brazilian Federation of Gastroenterology present the Fifth Brazilian Consensus on this topic, following the inaugural edition in 1995. Significant advances across various areas have emerged since the publication of the last consensus in 2018. These advances are particularly relevant to bacterial eradication, as treatment encounters mounting challenges due to rising antimicrobial resistance.
METHODS: For this update, five working groups were established to address: 1) epidemiology; 2) associated diseases and treatment indications; 3) diagnosis; 4) gastric cancer; and 5) treatment and microbiota.
CONCLUSION: The groups developed 34 evidence-based recommendations to guide clinicians in managing this infection within the Brazilian population.