Wenjie Fang, Xinyao Liu, Hazrat Bilal, Mohammad Daud Habib, Ahmed Nasir Hanifi, Nek Wali Shah Momin, Cornelia Lass-Flörl, Chin Samnang, Li An, Cunwei Cao, Min Chen, Zhongju Chen, Shuwen Deng, Li Fan, Jie Gong, Bing Gu, Jian Guo, Xiaoping Huang, Yingqian Kang, Guanzhao Liang, Likai Lin, Jiayun Liu, Weida Liu, Shiyuan Liu, Wei Liu, Zhengtu Li, Zhuozhe Li, Binghuai Lu, Zhiming Lu, Yuxing Ni, Xiaosong Qin, Haibo Qiu, Yiqing Qu, Dongmei Shi, Yi Shi, Xin Su, Hao Tang, Minggui Wang, Yong Wang, Junxue Wang, Wenjuan Wu, Bin Xu, Jinfu Xu, Yingchun Xu, Feng Ye, Yunsong Yu, Liping Zhu, Lin Zhou, Zhiyong Zong, Abdella Gemechu, Surajit De Mandal, Pratibha Gaur, Francesco Barchiesi, Giuseppina Caggiano, Bahareh Abbasi, Hamid Reza Jamaati, Shahla Mohammad Ganji, Sarah A Ahmed, Khaled Alobaid, Leslie Thian Lung Than, Abdullah M S Al-Hatmi, Afreenish Amir, Irum Mehmood, Matiur Rahman, Montarop Sudhadham, Macit İlkit, Pham Quynh Hoa, He Wang, Pham Hong Nhung, Thi Duyen Thi, Wanqing Liao, Xiaojun Huang, Weihua Pan
Invasive pulmonary fungal diseases (IPFD) continue to posing an increasing clinical and public health burden on immunocompromised populations. In many Asian settings, the diagnosis of IPFD faces substantial challenges driven by the high prevalence of comorbidities, including poorly controlled diabetes, tuberculosis (TB), and human immunodeficiency virus (HIV) infection, considerable heterogeneity in local pathogens, and disparities in access to diagnostic resources. To address these unmet needs, experts from 18 countries collaboratively developed this consensus, which provides a diagnostic algorithm tailored to high-burden Asian settings based on existing international and regional guidelines. When clinical manifestations are atypical or diagnostic clues are limited, the algorithm prioritizes evaluation for common and regionally prevalent IPFD, followed by stepwise expansion to other potential fungal pathogens. In addition, this consensus outlines the regional accessibility of different diagnostic modalities across Asia. This consensus focuses exclusively on optimization of the diagnostic algorithm and does not provide specific recommendations regarding antifungal therapy. Notably, improved diagnosis of IPFD through this algorithm may contribute to better patient outcomes and strengthened public health strategies in high-burden regions.