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◆ PloS one2026-01-01

Phobic anxiety disorders among patients with acne vulgaris at a national dermatology hospital in Vietnam: Prevalence, clinical phenotype, and associated factors.

Nguyen Van Tuan, Vu Thai Ha, Mai Son Duong

一句话结论 · In one sentence

In this tertiary-care sample, PADs-predominantly social phobia-were common. Associations with scarring, treatment response, physical comorbidity, and study-specific anxiety-proneness warrant confirmation in prospective multicentre studies using standardized psychosocial and treatment-response measures.

原始摘要(英文原文)· Original abstract
BACKGROUND: Acne vulgaris is associated with psychological morbidity, but clinically diagnosed phobic anxiety disorders (PADs) have been little studied in dermatology settings. METHODS: The analysis comprised 280 patients with acne vulgaris recruited by convenience sampling at a national dermatology hospital in Hanoi, Vietnam, from December 2025 to June 2026. A psychiatrist established PAD diagnoses using ICD-10 clinical criteria; Fear Questionnaire scores were used descriptively to characterize phobic symptoms among diagnosed cases. Multivariable logistic regression estimated adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for factors associated with PADs. RESULTS: PADs were diagnosed in 69 of 280 participants (24.6%; 95% CI, 20.0%-30.0%). Social phobia affected 64 participants (22.9% of the sample; 92.8% of PAD cases), specific phobia affected 26 (9.3%), and agoraphobia affected one (0.4%); subtypes could co-occur. In the exploratory adjusted model, PADs were associated with study-specific anxiety-proneness rating (aOR, 6.90; 95% CI, 2.92-16.32), physical comorbidity (aOR, 4.70; 95% CI, 2.30-9.60), acne scarring (aOR, 2.29; 95% CI, 1.04-5.05), and poor treatment response (aOR, 5.06; 95% CI, 2.20-11.62). Clinician-rated severe acne was not associated with PADs after adjustment. CONCLUSIONS: In this tertiary-care sample, PADs-predominantly social phobia-were common. Associations with scarring, treatment response, physical comorbidity, and study-specific anxiety-proneness warrant confirmation in prospective multicentre studies using standardized psychosocial and treatment-response measures.
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Phobic anxiety disorders among patients with acne vulgaris at a national dermatology hospital in Vietnam: Prevalence, clinical phenotype, and associated factors. — 科研速览 Science Skim