The people behind the papers - Udodirim (Udo) Saydee-Onwubiko and Amy Shaub Maddox.
原始摘要(英文原文)· Original abstract
Apoptosis during oogenesis is evolutionarily conserved across metazoans and is essential for eliminating defective developing oocytes, thereby maintaining tissue homeostasis and preventing pathologies such as cancer. In their work, Udodirim (Udo) Saydee-Onwubiko, Amy Shaub Maddox and colleagues resolve a previous conundrum in the field by revealing that apoptosis is essential for fertility and for maintaining the homeostatic germline architecture required for faithful oogenesis. To learn more about their work, we talked to the first author, Udodirim (Udo) Saydee-Onwubiko, as well as the corresponding author, Amy Shaub Maddox, Professor at the Department of Cell Biology and Physiology, UNC School of Medicine, USA.