Judith Tafur, Angelica Morales Cueva, Nicole E Familiari, Weronika E Stachera, Jeffrey B Woodruff
The eIF4ET family protein IFET-1 is needed for oocyte development and long-term storage in C. elegans . How IFET-1 plays multiple roles in oocyte biology is unclear. Using pull-downs and mass spectrometry, we identified proteins that interact with IFET-1 . We show that three IFET-1-interacting partners- PENR-1 , SQD-1 , and LSM-4 -are essential for producing viable oocytes in C. elegans females.