An urgent call to combat antimicrobial resistance in Sub-Saharan Africa through integrated and innovative solutions

Abstract Antimicrobial resistance (AMR) in Sub-Saharan Africa (SSA) represents a public health crisis that threatens treatment effectiveness and increases morbidity and mortality. This commentary highlights the urgent need for an integrated and collaborative approach among stakeholders to contain AMR, including strengthening healthcare infrastructure, promoting the rational use of antibiotics, and implementing effective monitoring policies. Adopting the One Health approach, investing in the continuous training of professionals, and leveraging innovative technologies such as artificial intelligence (AI) and machine learning (ML) are key strategies to mitigate the issue. However, challenges such as the scarcity of high-quality data still hinder the application of these solutions. Given this scenario, immediate and concrete actions are essential to prevent the worsening of AMR and ensure the sustainability of antimicrobial treatments in the region.