Prevalence, Associated Factors and Outcomes of Low-Birth-Weight Neonates in Kayunga: A Retrospective Cross Sectional Study

Introduction: Low birth weight (LBW) is a major contributor to neonatal mortality globally. In Uganda, a surge in LBW deliveries has been noted. Methods: This retrospective study assessed LBW prevalence, associated factors, and outcomes at Kayunga Regional Referral Hospital from February 2023 to February 2024. Of 1,177 neonatal admissions, 37.4% were LBW, with detailed analysis of 204 LBW weighing <2.0 kg requiring inpatient care. Data analyzed using STATA v15, logistic regression done for multivariate analysis. Ethical approval was obtained. Results: Lower gestational age (AOR = 333.04; 95% CI: 57.84-1917.53; P < .001), respiratory distress syndrome (AOR = 0.02; 95% CI: 0.01-0.29; P < .001) and apnea of prematurity (AOR = 0.08; 95% CI: 0.02-0.35; P < .001) were associated with LBW. Conclusion: Mortality was highest among very LBW (44.4%). The study highlights a high burden of LBW with poorer outcomes among very and extreme LBW neonates, underscoring the need to strengthen antenatal care and neonatal care services.