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◆ Tumori Journal2026-05-05· Mental health

The impact of bio-psycho-social factors on mental health outcomes in patients with solid tumors

Raffaela D.G. Sartori, Davide Dalu, Davide De Francesco, Valentina Biscaldi, Maria Silvia Cona, A. Gambaro, Sabrina Ferrario, Lorenzo Ruggieri, V. Filipazzi, Cinzia Fasola, Cristina Marrazzo, Nicla La Verde

原始摘要(英文原文)· Original abstract
INTRODUCTION: The old oncology approach, which considered the clinical and performance status as the most relevant diseases course and well-being indexes, has been recently replaced by a care system also focusing on a person's characteristics and needs. This study analyzed the role of physical symptoms, illness awareness, individual activities and social contexts on anxious/depressive symptoms and mental health in localized (LP) and advanced/metastatic (AMP) cancer patients. METHODS: Socio-demographic and medical information was gathered. The Revised Illness Perception Questionnaire, Hospital and Depression Anxiety Scale, and Mental Health Continuum Short-Form were administered. RESULTS: One hundred and thirteen patients, 75 LP and 38 AMP, aged 27-82, were enrolled. Unique patterns of difficulties and resources emerged at different stages of cancer. AMP reported a worse quality of life in perceived illness persistence and treatments control, anxious/depressive symptoms, and psychological well-being. In LP, higher levels of anxious/depressive symptoms were associated with lack of hobbies, and higher perceived illness control was linked to higher mental health. LP did not report higher well-being than AMP. No significant differences in flourishing persons distributions were detected among groups. A multivariable model showed that the independent presence of pain and partner influenced higher levels of mental health more in AMP than in LP. CONCLUSION: Tailored intervention should enhance individuals' mental health and active resources mobilization.
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The impact of bio-psycho-social factors on mental health outcomes in patients with solid tumors — 科研速览 Science Skim