S Mudasser Shah, Ghada Saleh Alhudaithi
IntroductionMental health stigma in Saudi Arabia is embedded in family honor, gendered role expectations, religiosity, privacy concerns, and help-seeking norms, but recent evidence has not been integrated around these mechanisms.MethodsWe systematically reviewed peer-reviewed primary empirical studies conducted in Saudi Arabia and published from 1 January 2020 through 31 March 2025. Searches of PubMed/MEDLINE, Scopus, Web of Science, PsycINFO, and EMBASE identified 1,019 database records, and citation chasing and hand-searching identified 23 additional records. A verification search on 7 December 2025 used the same strategy but did not extend the prespecified eligibility window. After deduplication and screening, 36 studies were included and synthesized using a convergent mixed-evidence thematic approach.ResultsAcross predominantly observational and cross-sectional evidence, stigma was associated more consistently with moralized weakness and role-risk narratives, particularly dangerousness, unreliability, and incompetence, than with overt supernatural causation alone. Family honor, gendered expectations, and marriageability concerns were associated with concealment, family gatekeeping, and social distance. Religiosity intersected with help-seeking mainly through privacy management and culturally acceptable framing. Intervention evidence was limited, short-term, and focused largely on knowledge or attitudes.ConclusionThe evidence identifies recurring sociocultural associations and plausible mechanisms rather than causal effects. Saudi stigma-reduction initiatives should target measurable behaviors, including social distance, disclosure safety, help-seeking, and discrimination in family, marriage, workplace, and healthcare settings, while using culturally appropriate family- and faith-sensitive designs.