Mid-term changes detected by corneal topography and optical coherence tomography after prophylactic laser iridotomy in primary angle closure suspect.

PURPOSE: To evaluate mid term changes in anterior segment parameters and to retinal layers by optical coherence tomography(OCT) in primary angle-closure suspected(PACS) after laser peripheral iridotomy(LPI). METHODS: For this retrospective study, 26 eyes of 26 subjects diagnosed with PACS and 20 eyes of 20 age and sex matched healthy people were enrolled. Anterior segment parameters [anterior chamber depth(ACD), anterior chamber volume(ACV), iridocorneal angle(ICA), central corneal thickness(CCT)] measured on Scheimpflug-Placido disc topography system and macular retinal thickness, peripapillary retinal nerve fiber layer(RNFL) thickness and macular ganglion cell-inner plexiform layer (GC-IPL) thickness measured on OCT. All the tests were repeated 1 month and 1 year after LPI. RESULTS: There was no significant difference between the groups in terms of age and gender. Anterior segment parameters during 1 year ACV, ICA increased, and CCT decreased significantly after LPI(p = 0.038, p = 0.038, and p = 0.020 respectively). A significant thinning of the inner inferior, outer nasal quadrants and the average of all quadrants of the retina was observed (p = 0.001, p = 0.009, and p = 0.001, respectively). The superior GC-IPL thinning was significant(p = 0.037). There was no significant change in the RNFL quadrants at the end of 1 year. CONCLUSION: Intraocular pressure can be kept under control with close follow-up in PACS cases and possible progression risk can be reduced by using tools such as laser peripheral iridotomy.