Madelyn Boslough, Matthew R G Taylor, Luisa Mestroni, Raffaela Lombardi
Dilated cardiomyopathy (DCM) is a leading cause of nonischemic heart failure. Genetic causes are identifiable in 25% to 30% of patients. This review describes the pathophysiology underlying genetic DCM, the genes most strongly associated with DCM, and both standard and novel therapies for treating genetic DCM.