How a Rare Inherited Lung Cancer Mutation Took Root in Appalachia.
原始摘要（英文原文）· Original abstract
A rare inherited EGFR mutation took root in Southern Appalachia after being carried to the United States by European settlers in the 1700s. Mapping the distribution of this germline EGFRT790M variant could help clinicians identify people at elevated risk of lung cancer and target them for genetic testing and closer surveillance.