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◆ ERJ open research2026-09-01

Autoimmune pulmonary alveolar proteinosis may not be invariably lifelong: exponential decay of anti-granulocyte-macrophage colony-stimulating factor autoantibodies over more than a decade.

Sinya Ohkouchi, Ryushi Tazawa, Takahiro Tanaka, Nobutaka Kitamura, Haruyuki Ishii, Koh Nakata

原始摘要(英文原文)· Original abstract
aPAP may not be lifelong: in three long-term cases, anti-GM-CSF autoantibodies peaked early then declined with exponential kinetics, disappearing after 7-16 years, suggesting eventual immune quiescence via attrition of long-lived plasma cells https://bit.ly/4n2m9No.
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Autoimmune pulmonary alveolar proteinosis may not be invariably lifelong: exponential decay of anti-granulocyte-macrophage colony-stimulating factor autoantibodies over more than a decade. — 科研速览 Science Skim