◆ American Journal of Physiology-Gastrointestinal and Liver Physiology2025-12-04· Dysbiosis
Microbial dysbiosis alters serotonin signaling in a postinflammatory murine model of visceral pain
Timothy D. Roth, Lillian Russo-Savage, Yasaman Bahojb Habibyan, Catherine M. Keenan, Laurie E. Wallace, Yasmin Nasser, Gary M. Mawe, Brigitte Lavoie, Keith A. Sharkey
原始摘要(英文原文)· Original abstract
The gut microbiota regulates serotonin biosynthesis in enterochromaffin cells. Here, we show that a dysbiotic gut microbiota that occurs after recovery from inflammation alters serotonin signaling and produces functional changes in enterochromaffin cell sensitivity.