Zhenghao Li, Zeyun Zhu, Shiran Lv, Xiaojun Guan, Yuyao Zhang, Cong Liu, D. Li, Hongjiang Wei
< .05). Subvoxel QSM enabled synucleinopathy differentiation (areas under receiver operating characteristic curve: PD vs HC, 0.87 [95% CI: 0.82, 0.92]; MSA vs HC, 0.94 [95% CI: 0.90, 0.98]; and PD vs MSA, 0.96 [95% CI: 0.93, 0.98]). Conclusion Subvoxel QSM enabled simultaneous measurement of α-Syn aggregation and iron deposition in patients with synucleinopathies, effectively distinguishing PD from MSA and both from HCs. © The Author(s) 2026. Published by the Radiological Society of North America under a CC BY 4.0 license.