Jochen K Lennerz, Fabio Del Ben, Albrecht Stenzinger, Katrin B M Frauenknecht, Anna Carobene, Nino Berishvili, João Tiago Guimarães, Luis Martí-Bonmatí, Reinhard Buettner, Verena Haselmann, Daniele Regge, Roberto Salgado, Mario Plebani, Pieter Vermeersch, Sergio Bernardini, Janne Cadamuro, Yale Tung-Chen, Norman Zerbe, Ian A Cree, Michael Neumaier, Regina Beets-Tan, Pilar Fernandez Calle, Miriam A Bredella, Tomris Ozben, European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Committee: Integrative Diagnostics
Integrated diagnostics is an emerging multidisciplinary model of care that integrates traditionally siloed domains, including pathology, radiology, genomics, and laboratory medicine, into a coordinated framework designed to improve diagnostic accuracy, treatment selection, and clinical outcomes. In this position statement, the EFLM Integrated Diagnostics Committee proposes a concise and operational definition of integrated diagnostics and outlines the relevance for healthcare systems. Integrated diagnostics has the potential to advance precision medicine through improved data integration, more coordinated interpretation, and enhanced clinical decision-making. Drawing on multidisciplinary expert consensus, we recommend adoption of a standardized conceptual framework to support research, clinical implementation, interoperability, and policy development across healthcare systems with implementation adapted to local needs, scale, and digital maturity.