Daniel C Sullivan, Michael McNitt-Gray, Denise R Aberle, Ricardo S Avila, Samuel G Armato, Paul M Bergstrom, Maria Chong, Dianna D Cody, Laura P Coombs, Richard A Frank, Robert J Gillies, Jonathan G Goldin, Jayashree Kalpathy-Cramer, Paul E Kinahan, Matthew B Schabath, Robert A Smith, David F Yankelevitz, Ella A Kazerooni
Lung cancer is the leading cause of cancer death in men and women. The goal of reducing mortality from lung cancer requires improvements in many aspects of the care pathway, beginning with early detection. Advances in imaging technologies and their application in clinical practice can contribute to addressing these challenges. As part of the American Cancer Society National Lung Cancer Roundtable's strategic plan, the roundtable's Advanced Imaging Across the Lung Cancer Care Continuum Task Group identified four advanced imaging technology topics as priority areas for development. These include novel (1) imaging technologies, (2) quantitative imaging biomarkers, (3) systems for sharing image data and/or algorithms, and (4) imaging-related artificial intelligence solutions. The authors provide background for each priority topic, describe key clinical problems along the lung cancer care pathway as use-case scenarios, and comment on challenges that impede implementation and dissemination of these potential advances.