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◆ BMJ case reports2026-08-18

Prenatal diagnosis of an isolated median cleft of the lower lip.

Matthieu Ortegat, Didier Van Wymersch, Peter Nardai, Khaled Mlik, Hélène Rixhon, Alexander Gerdom, Frédéric Debiève, Patricia Steenhaut

原始摘要(英文原文)· Original abstract
Orofacial clefts are among the most common congenital anomalies, typically involving the upper lip and palate. In contrast, clefts of the lower lip are exceptionally rare, with very few cases reported in the literature, particularly in the prenatal setting.We report a case of prenatal diagnosis of an isolated median cleft of the lower lip identified during the third trimester. This case highlights a rare congenital anomaly and underscores the importance of a thorough fetal facial assessment during routine ultrasounds.Prenatal diagnosis allows for appropriate perinatal planning and facilitates multidisciplinary counselling for optimal postnatal management.
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Prenatal diagnosis of an isolated median cleft of the lower lip. — 科研速览 Science Skim