Sadaf Soloukey, Daphna Hoefnagel, Mick de Vogel, Andries Paul Nagtegaal, Anne Kleijn
Pott's puffy tumour (PPT) is a rare condition defined by subperiosteal abscess formation following osteomyelitis of the frontal bone. Complications can be severe and involve intracranial progression.Here, we present a rare case of a PPT due to an Aggregatibacter aphrophilus infection of odontogenic origin in a young adult patient with a history of bilateral cheilognathopalatoschisis. Due to the unusual location of the abscess, the diagnosis was initially missed, leading to a delay of more than 1 month until adequate treatment. Odontogenic treatment was initiated as source control, external drainage of the abscess was performed and intravenous and later oral antibiotics were administered, which, despite relatively poor treatment adherence, ultimately led to adequate control of the infection without the need for further surgical intervention. The current case is the first report to highlight cleft palate-and consequent poorer oral health-as a potential predisposing condition for PPT.