DNA-Origami Apertured Tiles Self-Assembly and Surface AFM-Characterization in the Presence of Spontaneous Attachment of Single Colloidal Quantum Dot

Abstract Modern photonics technologies are increasingly dealing with nanostructures of different chemical composition and morphology. DNA-origami is one of the most promising methods of colloidal synthesis since its self-assembling allows creating organic nanoparticles with controlled geometry. Yet the issue remains how to hybridize them with single emitters of light for photonics applications. In the paper we investigate an opportunity of spontaneous interaction of DNA-origami in the form of parallelepiped tiles (61 × 52 × 5.8 nm) containing rectangle apertures (15 × 9 nm) with colloidal core-shell quantum dots (CdSe/CdS/ZnS/oleic acid). We characterize the attachment probability (~25%) as well as consider single DNA/QD hybrid geometry with atomic force microscopy using deep 2D deconvolution post-processing analysis for correction.