Genomic characterization of the attenuated human cytomegalovirus strain TR-VAC developed for subviral particle vaccine production.
Hanno Schmidt, Charlotte Hewel, Nicole Büscher, Matthias Linke, Bodo Plachter
原始摘要（英文原文）· Original abstract
We report the complete genome sequence of the attenuated human cytomegalovirus strain TR-VAC, developed for subviral particle vaccine production. Oxford Nanopore duplex sequencing confirmed all engineered modifications, including UL130 repair, UL25 stop codons, ddFKBP insertion, GFP deletion, and retention of the bacterial artificial chromosome backbone, without large-scale structural rearrangements.