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◆ Nature nanotechnology2026-08-14

Bioresorbable and optically readable triboelectric implants enabled by nanoscale iridophosphors.

Xiangchun Meng, Yong Hyun Kwon, Bojun Wang, Xiao Xiao, Jie Chen, Hyeon Mo, Yoojin Park, Sera Jeon, Eunbi Cho, Byung-Ok Choi, Peng Tao, Wai-Yeung Wong, Sang-Woo Kim

原始摘要(英文原文)· Original abstract
Implantable bioelectronics are typically inaccessible once implanted, and therefore structural damage, degradation and functional loss often go undetected until complications arise. Reliance on batteries further exacerbates these risks by imposing limited lifetimes, leakage hazards and non-resorbable components that may require surgical removal. Here we report a battery-free, bioresorbable triboelectric implant that enables externally readable, on-demand visualization of device status while generating electrical output. A data-driven materials-to-device workflow combines machine-learning-assisted photophysical screening with molecular-dipole-moment-based selection to identify nanoscale iridium(III) complexes optimized for both optical reporting and triboelectric charge generation. The resulting devices integrate a transcutaneous phosphorescent readout with ultrasound-driven energy harvesting, producing outlines visible to the unaided eye under handheld illumination and generating up to 3.6 Vpp at 0.5 W cm-2 of ultrasound power. In vivo studies in mice demonstrate that optical readouts track implant position, morphology and damage, correlate structural defects with loss of electrical output, and monitor integrity and bioresorption over 38 weeks. This work establishes a transient in vivo power platform whose morphology reports on structural integrity and energy-harvesting function, offering a route to observable bioelectronic implants and supporting timely intervention.
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Bioresorbable and optically readable triboelectric implants enabled by nanoscale iridophosphors. — 科研速览 Science Skim