Daridorexant- Case Report of Possible Side-Effect in Rare Mitochondrial Disorder.

This case report describes a 40-year-old woman with maternally inherited diabetes and deafness (MIDD), a rare mitochondrial disorder, who received treatment with daridorexant due to severe chronic insomnia. She developed progression of her MIDD symptoms during treatment. Caution is warranted when initiating daridorexant treatment in patients with mitochondrial disorders.