Sacrum Metastasis in Stage IA Endometrial Carcinoma 13 Years After Surgery: A Case Report.

Recurrence of early-stage endometrial cancer (EC) most commonly occurs within 5 years after initial surgery, and ultra-late recurrence more than 10 years after treatment is extremely rare. Bone metastasis from EC is also relatively uncommon. We report a case of Stage IA EC with sacral metastasis occurring 13 years after curative surgery. The patient is a 48-year-old woman who underwent radical hysterectomy for EC 13 years ago. She completed 5 years of follow-up with no recurrence. She was referred to our hospital because of a sacral tumor accompanied by pain and bladder and bowel dysfunction. A biopsy confirmed sacral metastasis from EC. Radiotherapy and chemotherapy resulted in improvement of neurological symptoms and tumor regression. This case highlights the potential efficacy of multidisciplinary treatment for not only the tumor but also neurological symptoms.