Highlights of 2025: Advances in the T‐Cell Regulation of Germinal Center Response

ABSTRACT In this 2025 Highlight, we summarize recent advances in T‐cell regulation of germinal center (GC) responses. These studies reveal new mechanisms governing follicular helper T (T FH )‐cell function and their control of GC dynamics and B‐cell fate decisions, providing insights for rational vaccine design and the prevention of GC dysregulation.