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◆ International journal of dermatology2026-08-07

Rethinking Corticosteroids in the Kligman-Willis Formula for Melasma.

Marina Landau, Jane M Grant-Kels, Fotini Bageorgou, Rashmi Sarkar, Mohamad Goldust

原始摘要(英文原文)· Original abstract
Melasma necessitates effective long-term management that goes beyond initial treatment. Although the Kligman-Willis triple combination is the standard induction therapy, prolonged use of corticosteroids raises safety concerns. We propose a maintenance strategy that spares corticosteroids while still utilizing a formulation that has been proven over the years to be the most effective for treating melasma. This approach aims to enhance safety by omitting corticosteroids.
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Rethinking Corticosteroids in the Kligman-Willis Formula for Melasma. — 科研速览 Science Skim