◆ European Journal of Clinical Investigation2026-05-01· Fibroblast
Ferroptosis‐Associated Fibroblast Activation and Transcriptional Remodelling in Human Heart Failure: A Proof‐of‐Concept Study
Konstantinos Karampinos, Georgios Georgiopoulos, Marinos Kallikourdis, Rijan Gurung, Roger Foo, D Cokkinos, Dimitrios Farmakis
原始摘要（英文原文）· Original abstract
Single-cell analysis of human heart failure identifies a fibroblast-enriched ferroptosis signature that distinguishes DCM from controls and reveals a pseudotime trajectory linking ferroptotic stress to progressive fibroblast activation and pro-fibrotic remodelling.