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◆ Clinical, cosmetic and investigational dermatology2026-01-01

The Role of Dermocosmetics in Acne Management: Implications for Clinical Practice in Brazil.

Marco Alexandre Da Rocha, Ediléia Bagatin, Brigitte Dréno, Gabriel Gontijo, Beatriz Medeiros Ribeiro, Luiz Mauricio C Almeida

原始摘要(英文原文)· Original abstract
Acne is a prevalent skin condition worldwide, affecting diverse populations, including Brazil. Although acne guidelines are well established for topical and/or systemic medications, recommendations regarding dermocosmetics, which have become increasingly important in acne management, remain limited. This review examines the role of dermocosmetics within acne treatment protocols and provides practical guidance for their integration into skincare routines alongside conventional therapies. Six dermatology experts conducted structured PubMed literature searches (2012-2024) and discussed the findings during expert meetings focused on acne management and dermocosmetics in the Brazilian context. Despite increasing evidence of benefit, the role of dermocosmetics remains underreported, with systemic treatments predominating. Acne pathophysiology is complex with four main pillars: hyperkeratinization of the pilosebaceous gland infundibulum, inflammation, overactivity of sebaceous glands, and microbiome imbalance in the context of an altered skin barrier. Advances in acne microbiome research highlight the importance of targeting dysbiosis, with new treatments exploring pre-, pro-, and postbiotics and bacteriophages. Dermocosmetics containing key active ingredients can address these multifactorial targets of acne, including excessive sebum production, hyperkeratinization, inflammation, and skin barrier and microbiome imbalance. They have been shown in clinical studies to be beneficial as monotherapy for mild cases, as maintenance therapy, or as adjuncts to acne medications. Due to their safety and tolerability profile, dermocosmetics are especially valuable for specific populations, such as pregnant women and prepubertal patients. Published evidence and expert clinical consensus support integrating dermocosmetics into daily routines to enhance acne control, patient adherence, and quality of life. Effective patient education on skincare regimens prevents treatment-related issues and optimizes outcomes. Incorporating dermocosmetics and improving patient education may further optimize these benefits.
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The Role of Dermocosmetics in Acne Management: Implications for Clinical Practice in Brazil. — 科研速览 Science Skim