Ilse Andrea Moreno-Arquieta, Héctor Teodoro Rios-Bazaldua, Roger Adrián González-Ramírez, Gabriel Salerni, Erika Stephania Alvarado-Arana, José Alberto García-Lozano, Juan Pablo Gonzalez-Morales, Jesus Alberto Cardenas-de la Garza
Monkeypox (mpox) is a viral infection characterized by polymorphic cutaneous lesions and systemic symptoms, including fever, lymphadenopathy, headache and myalgia. Given its broad differential diagnosis, accurate recognition requires a high level of clinical suspicion; in this context, dermoscopy represents a potentially useful tool to improve diagnostic accuracy. We conducted a retrospective case series of six patients with RT-PCR-confirmed mpox and dermatologic involvement between July 2022 and July 2025. A total of six patients were included; three (50%) were evaluated in the macular/vesicular phase and three (50%) in the crusted phase. In the macular/vesicular phase, eight lesions were analysed. In the crusted phase, five lesions were analysed. In our series, we observed pinkish-yellow structureless areas during the macular/vesicular phase. Recognition of these dermoscopic features may increase clinical suspicion and support the diagnosis.